VETERINARY MEDICINAL PRODUCTS ASD DOROGOVA
CHEMICAL AND PHARMACOLOGICAL CHARACTERISTICS OF THE DRUG ASD
ASD fraction 2 and ASD fraction 3 are products of deep thermal decomposition of the protein and contain low molecular weight nitrogenous organic and inorganic compounds. The ASD fraction 2 contains low-boiling fatty carboxylic acids in the form of ammonium salts and amides. The composition of ASD fraction 3 includes neutral compounds of hydrocarbons and ketones, pyridine bases and phenols. All these compounds lose their affinity for the original protein and have neither histological nor species specificity. They are not exposed to the action of proteolytic enzymes of the gastrointestinal tract (since the latter are not able to break down protein so deeply) and are absorbed into the blood unchanged. The biochemical mechanism of the pharmacological action of these low molecular weight compounds on the body has not yet been elucidated.
The drug has a multifaceted effect on the body. It increases metabolism and oxidative processes, increases reserve alkalinity in the blood, which contributes to the normalization of metabolism in tissues, improves digestion, absorption of nutrients, stimulates the activity of the heart and respiration, stimulates the growth and development of young children. animals. The drug causes an improvement in the functional state of the mechanisms of natural resistance, enhances the processes of tissue regeneration, stimulates immunogenesis, resulting in increased resistance to adverse effects, including pathogens of infectious diseases.
Stimulation of physiological functions and immunobiological reactions is carried out through the nervous system, which responds to the introduction of very small doses of the drug. The high sensitivity of the nervous system, apparently, is due to a change in the activity of its enzyme systems, primarily redox enzymes.
Stimulation of the growth of animals and the restoration of the disturbed deception of substances in sick animals indicates that the drug increases the synthetic processes in the body. Apparently, the stimulating effect of ASD is due to the accumulation of biologically active complexes, including enzymes, in the body of animals.
HISTORY OF CREATION
In 1943, the leadership of the USSR set dozens of laboratories at institutes, academies, and universities with a secret government task - to develop a drug that protects people and animals from radiation. The drug was supposed not only to increase immunity, but also to be cheap. Harsh conditions baffled many scientists and researchers. Success fell to the lot of the laboratory of the All-Union Institute of Experimental Veterinary Medicine (VIEV), headed by A.V. Dorogov, Candidate of Veterinary Sciences.
It is possible that it was the unconventional approach to solving problems and the talent for exploration of Alexei Dorogov that brought him luck. It is possible that the young scientist remembered the ancient healers and their methods of making "miraculous" potions. Be that as it may, the scientist used frogs as a biological raw material, and as a processing method, high-temperature sublimation of tissues, followed by condensation of the resulting vapors. The resulting liquid had antiseptic, stimulating, wound-healing properties and was named Dorogov's Antiseptic Stimulator - ASD. Subsequently, the liquid settled and stratified - the precipitate was called ASD fraction 3, and the liquid above the sediment was called ASD fraction 2.
FKP "Armavir biofactory" began its history in 1919. The main activity is the development and production of drugs for the treatment of animals and humans. The number of the enterprise exceeds 630 employees. The assortment of the enterprise includes more than 80 types of products. Also in the arsenal there are various auxiliary agricultural production. The production of medicines in the Armavir biofactory is carried out in accordance with European standards (GMP). Quality control and management is carried out, and production facilities and personnel comply with the requirements of European production standards.
DOROGOV'S ANTISEPTIC STIMULATOR, FRACTION 2 BIOLOGICAL PROPERTIES:
ASD fraction 2 is a product of dry distillation of raw materials of animal origin. When administered orally, it activates the central and autonomic nervous systems (CNS and ANS), stimulates the motor activity of the gastrointestinal tract (GIT), the secretion of digestive glands, increases the activity of digestive and tissue enzymes, improves the penetration of Na + and K + through cell membranes. Helps normalize digestion and absorption of nutrients, as well as increase the body's natural resistance.
When applied externally, the drug stimulates the activity of the reticuloendothelial system (RES), normalizes trophism and accelerates the restoration of damaged tissues, has a pronounced antiseptic and anti-inflammatory effect.
DOROGOV'S ANTISEPTIC STIMULATOR, FRACTION 3 PHARMACOLOGICAL PROPERTIES:
ASD fraction 3 refers to tissue preparations. Obtained by dry distillation of tissues of animal origin. The drug enhances the body's immunity, has a pronounced antiseptic effect, stimulates the activity of the reticuloendothelial and endocrine systems, normalizes trophism, accelerates the regeneration of damaged tissues, does not have a cumulative effect. ASD fraction 3, according to the degree of impact on the body, belongs to moderately hazardous substances.
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